Enlarged striatum in abstinent methamphetamine abusers: A possible compensatory response
نویسندگان
چکیده
منابع مشابه
Decreased frontal white-matter integrity in abstinent methamphetamine abusers.
This study explored differences in frontal white-matter (WM) integrity between methamphetamine (MA) abusers and healthy comparison subjects using diffusion tensor imaging (DTI). Fractional anisotropy (FA) values, which indicate WM integrity, were calculated for regions-of-interest in frontal WM on diffusion tensor images of 32 MA abusers and 30 healthy comparison subjects. Frontal executive fun...
متن کاملPrefrontal grey-matter changes in short-term and long-term abstinent methamphetamine abusers.
Authors explored grey-matter density in 29 methamphetamine abusers and 20 healthy comparison subjects using voxel-based morphometry. Grey-matter density changes and performances on the Wisconsin Card Sorting test (WCST) were also compared between 11 short-term (<6 months) and 18 long-term (>or=6 months) abstinent methamphetamine abusers. Methamphetamine abusers had lower grey-matter density in ...
متن کاملPrefrontal cortical dysfunction in abstinent cocaine abusers.
The anterior cingulate cortex (ACC) and lateral prefrontal (LPFC) cortex are brain regions important to executive cognitive functions (ECF). We determined ACC and LPFC function in 23-day abstinent cocaine abusers using positron emission tomography (PET H(2)(15)O) during performance of a modified version of the Stroop Task. Cocaine abusers showed less activation than non-drug-using comparison su...
متن کاملMetabolic Abnormalities in Abstinent Methamphetamine Dependent Subjects
INTRODUCTION: Chronic methamphetamine use results in persistent neuropsychological deficits in abstinent methamphetamine dependent (AMD) subjects. We examined the hypothesis that elevated concentration of cerebral glutamate (Glu), an excitatory neurotransmitter and neurotoxin, occurs in human AMD. MATERIALS AND METHODS: We examined 40 subjects, 18 of whom were AMD, abstinent more than 3 weeks ...
متن کاملDeclarative and procedural memory functioning in abstinent cocaine abusers.
BACKGROUND We determined the nature and recovery of procedural and declarative memory functioning in a cocaine-abusing cohort in the 45-day period following use. METHODS Thirty-seven cocaine abusers and 27 control subjects were administered the following memory and mood measures: California Verbal Learning Test, recall of the Rey-Osterrieth Complex Figure Test, Pursuit Rotor Task, and Profile...
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ژورنال
عنوان ژورنال: Biological Psychiatry
سال: 2005
ISSN: 0006-3223
DOI: 10.1016/j.biopsych.2005.01.039